Development of inactivated cultural yellow fever vaccine
نویسندگان
چکیده
منابع مشابه
17DD yellow fever vaccine
OBJECTIVE To verify if the Bio-Manguinhos 17DD yellow fever vaccine (17DD-YFV) used in lower doses is as immunogenic and safe as the current formulation. RESULTS Doses from 27,476 IU to 587 IU induced similar seroconversion rates and neutralizing antibodies geometric mean titers (GMTs). Immunity of those who seroconverted to YF was maintained for 10 mo. Reactogenicity was low for all groups. ...
متن کاملYellow fever vaccine.
only faces almost insurmountable problems as it tries to form a new government, it also faces many serious health issues including sexually transmitted diseases (STDs). Surveillance data from the Ukrainian STD Center from January 1, 1989, through December 31, 1995, were analyzed on the basis of reports received through 1997. In western Europe, the incidence of syphilis and gonorrhea declined fr...
متن کاملYF-VAX, Yellow Fever Vaccine
DESCRIPTION YF-VAX®, Yellow Fever Vaccine, for subcutaneous use, is prepared by culturing the 17D-204 strain of yellow fever virus in living avian leukosis virus-free (ALV-free) chicken embryos. The vaccine contains sorbitol and gelatin as a stabilizer, is lyophilized, and is hermetically sealed under nitrogen. No preservative is added. The vaccine must be reconstituted immediately before use w...
متن کامل17D Yellow Fever Virus Vaccine
Dear Sir: In a recent article, Edupuganti and others reported a clinical study of co-administration of subcutaneous yellow fever (YF) 17D vaccine (YF-VAX Ò ; Sanofi Pasteur, Lyon, France) and intramuscular immune serum globulin (ISG) (amaSTAN S/D Ò ; Talecris Biotherapeutics, Research Triangle Park, NC) or saline placebo. 1 The study was designed to test whether co-administration of vaccine and...
متن کاملA DNA Vaccine against Yellow Fever Virus: Development and Evaluation
Attenuated yellow fever (YF) virus 17D/17DD vaccines are the only available protection from YF infection, which remains a significant source of morbidity and mortality in the tropical areas of the world. The attenuated YF virus vaccine, which is used worldwide, generates both long-lasting neutralizing antibodies and strong T-cell responses. However, on rare occasions, this vaccine has toxic sid...
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ژورنال
عنوان ژورنال: Problems of Virology Russian journal
سال: 2020
ISSN: 2411-2097,0507-4088
DOI: 10.36233/0507-4088-2020-65-4-212-217